Microgravity decreases and hypergravity increases exhaled nitric oxide
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چکیده
منابع مشابه
Microgravity decreases and hypergravity increases exhaled nitric oxide.
Inhalation of toxic dust during planetary space missions may cause airway inflammation, which can be monitored with exhaled nitric oxide (NO). Gravity will differ from earth, and we hypothesized that gravity changes would influence exhaled NO by altering lung diffusing capacity and alveolar uptake of NO. Five subjects were studied during microgravity aboard the International Space Station, and ...
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BACKGROUND Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) production. It was therefore hypothesised that caffeine may alter exhaled NO (eNO) levels. METHODS In a randomised, single blind, crossover manner, 12 normal subjects consumed either (1) coffee a...
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BACKGROUND Exhaled nitric oxide (FeNO) is a well described marker of airway inflammation in asthma and is also known to increase after chronic exposure to inhaled allergens. It is not known whether monitoring FeNO could be useful during food challenges to detect early or subclinical reactions. METHODS Forty children aged 3 to 16 years undergoing an allergen-food challenge at two centres were ...
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BACKGROUND The human airway is believed to be acidified in asthma. In an acidic environment nitrite is converted to nitric oxide (NO). OBJECTIVE We hypothesized that buffering airway lining fluid acid would decrease the fraction of exhaled NO (F(ENO)). METHODS We treated 28 adult nonsmoking subjects (9 healthy control subjects, 11 subjects with mild intermittent asthma, and 8 subjects with ...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2009
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.91081.2008